FRAT IgG Test

Folate Receptor Autoantibody Test (FRAT)

The FRAT IgG Test (Folate Receptor Autoantibody Test) is a specialized blood test that helps identify whether folate receptor autoantibodies are interfering with the transport of folate (Vitamin B9) into the brain. Folate plays a critical role in brain development, speech, cognition, attention, behavior, and neurological function.

Research has shown that a significant percentage of children on the autism spectrum may have folate receptor autoantibodies, which can affect how folate reaches the brain even when blood folate levels appear normal.

Why is the FRAT Test Important in Autism?

Many children on the spectrum may experience challenges related to:

• Speech and language delay
• Attention and focus difficulties
• Behavioral dysregulation
• Sensory concerns
• Developmental delays
• Cognitive and learning challenges

In some children, impaired folate transport to the brain may be one of the contributing biological factors. The FRAT IgG Test helps identify this possibility and supports deeper clinical understanding.

These tests are helpful for:

✔️Children with speech delay, ASD, ADHD, or sensory issues

✔️Developmental delay

✔️Attention and behavioral concerns

✔️Regression or learning challenges

A blood sample is required for the FRAT IgG Test. Blood sample collection is available Pan India from the comfort of your doorstep.

There is no strict minimum age for the FRAT IgG Test. It is commonly considered for young children showing early signs of developmental concerns such as speech delay, autism-related symptoms, regression, attention difficulties, or developmental delays. The test should always be considered under the guidance of a qualified healthcare professional.

All India

No. The FRAT Test is not a diagnostic test for autism. It is an advanced biomarker test that may provide additional insights into folate transport and neurodevelopmental functioning.

Early identification may help clinicians and families explore more targeted nutritional and medical approaches during important developmental years.